NIH #7R01DK130174-04
Developing proinsulin misfolding inhibitors for beta cell protection and diabetes treatment
Active
- Amount
- $NaNK
- Period
- 2025-06-01 → 2027-05-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF ALABAMA AT BIRMINGHAM
NIH #5R01DK130174-02
Developing proinsulin misfolding inhibitors for beta cell protection and diabetes treatment
Active
- Amount
- $NaNK
- Period
- 2022-07-15 → 2027-05-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #1R01DK130174-01A1
Developing proinsulin misfolding inhibitors for beta cell protection and diabetes treatment
Active
- Amount
- $NaNK
- Period
- 2022-07-15 → 2027-05-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #7R01DK128848-05
Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment
Active
- Amount
- $NaNK
- Period
- 2021-06-15 → 2027-03-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF ALABAMA AT BIRMINGHAM
NIH #5R01DK128848-03
Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment
- Amount
- $NaNK
- Period
- 2021-06-15 → 2026-03-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #5R01DK128848-02
Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment
- Amount
- $NaNK
- Period
- 2021-06-15 → 2026-03-31
- PIs
- 2
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #1R01DK128848-01
Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment
- Amount
- $NaNK
- Period
- 2021-06-15 → 2026-03-31
- PIs
- 2
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #5R01DK130174-03
Developing proinsulin misfolding inhibitors for beta cell protection and diabetes treatment
- Amount
- $NaNK
- Period
- 2022-07-15 → 2025-05-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #5R01DK128848-04
Preclinical Validation of PPARg Acetylation Inhibitors for Diabetes Prevention and Treatment
- Amount
- $NaNK
- Period
- 2021-06-15 → 2025-03-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #5R01DK116017-04
Cytoprotection and the mechanism of action of a natural product Khellin against ER stress
- Amount
- $NaNK
- Period
- 2018-08-01 → 2024-05-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #3R01DK116017-03S1
Cytoprotection and the mechanism of action of a natural product Khellin against ER stress
- Amount
- $NaNK
- Period
- 2018-08-01 → 2022-05-31
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
NIH #1ZIAAG000486-05
Investigating a novel shelterin-associated protein complex in telomere protection
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000495-04
Investigating the roles of RNA-binding proteins Nocte and PRRC2 in mRNA translation and age-related neurodegeneration using Drosophila and mouse models
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000501-03
Investigating the roles of a Topoisomerase complex in autophagy and lifespan regulation
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000447-02
Investigating roles of Topoisomerase 3b (TOP3B) in LPS-induced microglia-mediated neuroinflammation in mouse
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000686-06
Investigation of whether Topoisomerase 3b can be a drug target for SARS-CoV-2 and other positive-strand RNA virus; and development of such a drug
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000559-01
Investigating roles of the Top3b-Tdrd3 complex in regulation of sleep and circadian rhythms in mental health disorders
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000688-24
Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000689-15
An RNA topoisomerase complex interacts with Fragile X syndrome protein to promote neurodevelopment and maintain normal life-span
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000688-23
Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000692-05
ALZHEIMERS RESEARCH PROJECT: Investigating the roles of Topoisomerase 3b-TDRD3 complex in neurodegeneration and Alzheimer's disease
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000447-01
Investigating roles of Topoisomerase 3b (TOP3B) in LPS-induced microglia-mediated neuroinflammation in mouse
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000502-02
Investigating roles of Topoisomerase 3b (TOP3B) in immune responses to infection by coronavirus and bacteria
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000686-05
Investigation of whether Topoisomerase 3b can be a drug target for SARS-CoV-2 and other positive-strand RNA virus; and development of such a drug
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000486-04
Investigating a novel shelterin-associated protein complex in telomere protection
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000495-03
Investigating the roles of RNA-binding proteins Nocte and PRRC2 in mRNA translation and age-related neurodegeneration using Drosophila and mouse models
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000501-02
Investigating the roles of a Topoisomerase complex in autophagy and lifespan regulation
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000689-14
An RNA topoisomerase complex interacts with Fragile X syndrome protein to promote neurodevelopment and maintain normal life-span
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000486-03
Investigating a novel shelterin-associated protein complex in telomere protection
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000689-13
An RNA topoisomerase complex interacts with Fragile X syndrome protein to promote neurodevelopment and maintain normal life-span
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000495-02
Investigating the roles of RNA-binding proteins Nocte and PRRC2 in mRNA translation and age-related neurodegeneration using Drosophila and mouse models
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000692-04
Investigating the roles of Topoisomerase 3b-TDRD3 complex in neurodegeneration and Alzheimer's disease
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000501-01
Investigating the roles of a Topoisomerase complex in autophagy and lifespan regulation
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000686-04
Investigation of whether Topoisomerase 3b can be a drug target for SARS-CoV-2 and other positive-strand RNA virus; and development of such a drug
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000688-22
Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000502-01
Investigating roles of Topoisomerase 3b (TOP3B) in immune responses to infection by coronavirus and bacteria
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000486-02
Investigating a novel shelterin-associated protein complex in telomere protection
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000688-21
Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000692-03
Investigating the roles of Topoisomerase 3b-TDRD3 complex in neurodegeneration and Alzheimer's disease
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000689-12
An RNA topoisomerase complex interacts with Fragile X syndrome protein to promote neurodevelopment and maintain normal life-span
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000495-01
Investigating the roles of RNA-binding proteins Nocte and PRRC2 in mRNA translation and age-related neurodegeneration using Drosophila and mouse models
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000686-03
Investigation of whether Topoisomerase 3b can be a drug target for SARS-CoV-2 and other positive-strand RNA virus; and development of such a drug
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000650-13
Structural And Functional Studies Of Human Swi/snf Chromatin-remodeling
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000486-01
Investigating a novel shelterin-associated protein complex in telomere protection
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000688-20
Investigate the DNA damage response pathway of Fanconi anemia and BRCA proteins
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000689-11
An RNA topoisomerase complex interacts with Fragile X syndrome protein to promote neurodevelopment and maintain normal life-span
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000657-22
Identification and characterization Of A Complex Involved In Bloom Syndrome
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000686-02
Investigation of whether Topoisomerase 3b can be a drug target for SARS-CoV-2 and other positive-strand RNA virus; and development of such a drug
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000692-02
Investigating the roles of Topoisomerase 3b-TDRD3 complex in neurodegeneration and Alzheimer's disease
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING
NIH #1ZIAAG000686-01
Investigation of whether Topoisomerase 3b can be a drug target for SARS-CoV-2 and other positive-strand RNA virus; and development of such a drug
- Amount
- $NaNK
- Period
- — → —
- PIs
- 1
- Est. capacity / PI
- ~ students
Awarded at NATIONAL INSTITUTE ON AGING