Xavier Darzacq

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Unstructured transcription factor interactions enable emergent specificity

  Science · 2026-03-19 · 7 citations

• Data for: Unstructured Transcription Factor Interactions Enable Emergent Specificity

  Zenodo (CERN European Organization for Nuclear Research) · 2026-03-13

• Data for: Unstructured Transcription Factor Interactions Enable Emergent Specificity

  Zenodo (CERN European Organization for Nuclear Research) · 2026-03-13

• BPS2026 – Exclusive protein interactions are responsible for functional competition

  Biophysical Journal · 2026-02-01

• BPS2026 - Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

  Biophysical Journal · 2026-02-01

• BPS2026 – Live-cell single-molecule dynamics reveals spatiotemporal transcriptional modulation by the BAF chromatin remodeler

  Biophysical Journal · 2026-02-01

• Short activation domains control chromatin association of transcription factors

  eLife · 2025-11-21 · 1 citations

• Elevated MyoD1 levels expand genome-wide binding and the repertoire of regulated genesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-11-14

• Author response: Short activation domains control chromatin association of transcription factors

  2025-08-26

• Single-molecule live imaging of subunit interactions and exchange within cellular regulatory complexes

  Molecular Cell · 2025-07-23 · 7 citations

• Transcriptional programs of cell identity and p53-induced stress responses are associated with distinctive features of spatial genome organization

  Nucleic Acids Research · 2025-06-13 · 2 citations

• Bis(trifluoromethyl)carborhodamines: Highly Fluorogenic, Far-Red to Near-Infrared Dyes for Live Cell Fluorescence Microscopy, Activity-Based Sensing, and Single-Molecule Microscopy

  Journal of the American Chemical Society · 2025-06-12 · 11 citations

• bis(trifluoromethyl)-carborhodamines: highly fluorogenic, far-red to near infrared dyes for live cell fluorescence microscopy, activity-based sensing, and single-molecule microscopyPreprint

  ChemRxiv · 2025-04-03

• Assembly and Dynamics of Transcription Initiation Complexes

  Annual Review of Biochemistry · 2025-03-25 · 7 citations

• Oblique line scan illumination enables expansive, accurate and sensitive single-protein measurements in solution and in living cells

  Nature Methods · 2025-02-18 · 16 citations

• Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors

  Nature Communications · 2025-02-11 · 6 citations

• Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

  eLife · 2025-01-10 · 7 citations

• Author response: Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

  2025-01-10

• Author response: A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

  2025-01-09

• Short activation domains control chromatin association of transcription factorsPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-12-22 · 2 citations