Full Professor(heuristic)

Epigenetics and DNA Methylation · Molecular Biology

h-index89
i10-index264
Publications510
Citations30,042

Grants

50 total · 13 active

NIH #1R01AG091781-01A1

Epac1 Signaling Promotes Retinal Neuronal Injury During Tauopathy

Active
Amount
$617K
Period
2026-06-152031-03-31
PIs
2
Est. capacity / PI
~5 students

Awarded at UNIVERSITY OF TEXAS MED BR GALVESTON

NIH #5R35GM134744-07

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Active
Amount
$660K
Period
2020-01-012030-03-31
PIs
1
Est. capacity / PI
~4 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #2R35GM134744-06

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Active
Amount
$660K
Period
2020-01-012030-03-31
PIs
1
Est. capacity / PI
~4 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

Student capacity is a rough estimate from remaining award size, split equally among PIs. Actual funding decisions vary.

All Grants

50 total · 13 active

NIH #1R01AG091781-01A1

Epac1 Signaling Promotes Retinal Neuronal Injury During Tauopathy

Active
Amount
$617K
Period
2026-06-152031-03-31
PIs
2
Est. capacity / PI
~5 students

Awarded at UNIVERSITY OF TEXAS MED BR GALVESTON

NIH #5R35GM134744-07

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Active
Amount
$660K
Period
2020-01-012030-03-31
PIs
1
Est. capacity / PI
~4 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #2R35GM134744-06

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Active
Amount
$660K
Period
2020-01-012030-03-31
PIs
1
Est. capacity / PI
~4 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R01DK136462-02

Significance of Epac signaling in renal Na+handling and hypertension

Active
Amount
$679K
Period
2024-08-192028-06-30
PIs
2
Est. capacity / PI
~2 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #1R01DK136462-01A1

Significance of Epac signaling in renal Na+handling and hypertension

Active
Amount
$679K
Period
2024-08-192028-06-30
PIs
2
Est. capacity / PI
~2 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01EY033319-04

Epac1 as a novel therapeutic target for diabetic retinopathy

Active
Amount
$506K
Period
2022-09-012027-06-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01EY033319-03

Epac1 as a novel therapeutic target for diabetic retinopathy

Active
Amount
$506K
Period
2022-09-012027-06-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01EY033319-02

Epac1 as a novel therapeutic target for diabetic retinopathy

Active
Amount
$506K
Period
2022-09-012027-06-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #1R01EY033319-01A1

Epac1 as a novel therapeutic target for diabetic retinopathy

Active
Amount
$515K
Period
2022-09-012027-06-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01DK132286-04

Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis

Active
Amount
$436K
Period
2023-03-012026-12-31
PIs
2
Est. capacity / PI
~0 students

Awarded at TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR

NIH #5R01DK132286-03

Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis

Active
Amount
$437K
Period
2023-03-012026-12-31
PIs
2
Est. capacity / PI
~0 students

Awarded at TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR

NIH #5R01DK132286-02

Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis

Active
Amount
$422K
Period
2023-03-012026-12-31
PIs
2
Est. capacity / PI
~0 students

Awarded at TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR

NIH #1R01DK132286-01A1

Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis

Active
Amount
$445K
Period
2023-03-012026-12-31
PIs
2
Est. capacity / PI
~0 students

Awarded at TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR

NIH #3R01EY033319-03S1

Epac1 as a novel therapeutic target for diabetic retinopathy

Amount
$40K
Period
2025-07-012026-06-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R21CA277152-02

Preclinical studies of non-nucleoside DNMT3A/3B inhibitors

Amount
$189K
Period
2023-12-192025-11-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #1R21CA277152-01A1

Preclinical studies of non-nucleoside DNMT3A/3B inhibitors

Amount
$227K
Period
2023-12-192025-11-30
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R35GM134744-05

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Amount
$585K
Period
2020-01-012025-03-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R35GM134744-04

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Amount
$585K
Period
2020-01-012024-12-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #3R35GM134744-04S1

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Amount
$250K
Period
2020-01-012024-12-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R35GM134744-03

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Amount
$585K
Period
2020-01-012024-12-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R35GM134744-02

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Amount
$585K
Period
2020-01-012024-12-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #1R35GM134744-01

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Amount
$585K
Period
2020-01-012024-12-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #1R56DK136462-01

Significance of Epac signaling in renal Na+ handling and hypertension

Amount
$150K
Period
2023-08-152024-07-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5P30CA016672-47

25 Cancer Genetics and Epigenetics

Amount
$19K
Period
1996-08-282024-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5P30CA016672-46

25 Cancer Genetics and Epigenetics

Amount
$19K
Period
1996-08-282024-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5P30CA016672-45

25 Cancer Genetics and Epigenetics

Amount
$19K
Period
1996-08-282024-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R35GM122536-05

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$429K
Period
2017-07-012023-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #3R35GM122536-03S1

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$48K
Period
2017-07-012022-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R35GM122536-04

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$429K
Period
2017-07-012022-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R35GM122536-03

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$429K
Period
2017-07-012022-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R35GM122536-02

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$429K
Period
2017-07-012022-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #1R35GM122536-01

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$115K
Period
2017-07-012022-06-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01AI111464-05

Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

Amount
$1.2M
Period
2014-04-102021-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #7R01GM049245-24

DNA Methylation: Structures, Functions and Regulation

Amount
$497K
Period
1993-04-012020-07-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R01GM114306-05

Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms

Amount
$295K
Period
2015-04-012020-03-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R01GM066170-15

Epac/cAMP-GEF, A Novel Intracellular cAMP Receptor

Amount
$373K
Period
2003-05-012019-04-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01AI111464-04

Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

Amount
$1.2M
Period
2014-04-102019-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #7R01GM114306-04

Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms

Amount
$310K
Period
2015-04-012019-03-31
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #5R01AI111464-03

Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

Amount
$1.3M
Period
2014-04-102019-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01GM114306-02

Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms

Amount
$289K
Period
2015-04-012019-03-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EMORY UNIVERSITY

NIH #5R01AI111464-02

Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

Amount
$1.3M
Period
2014-04-102019-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #1R01GM114306-01

Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms

Amount
$303K
Period
2015-04-012019-03-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EMORY UNIVERSITY

NIH #1R01AI111464-01

Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

Amount
$1.5M
Period
2014-04-102019-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #3R01GM049245-22S1

DNA Methylation: Structures, Functions and Regulation

Amount
$75K
Period
1993-04-012018-07-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EMORY UNIVERSITY

NIH #5R01GM049245-22

DNA Methylation: Structures, Functions and Regulation

Amount
$388K
Period
1993-04-012018-07-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EMORY UNIVERSITY

NIH #5R01GM066170-14

Epac/cAMP-GEF, A Novel Intracellular cAMP Receptor

Amount
$373K
Period
2003-05-012018-04-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #5R01GM066170-13

Epac/cAMP-GEF, A Novel Intracellular cAMP Receptor

Amount
$373K
Period
2003-05-012018-04-30
PIs
1
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #3R01GM049245-23S1

DNA Methylation: Structures, Functions and Regulation

Amount
$138K
Period
1993-04-012017-07-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EMORY UNIVERSITY

NIH #5R01GM049245-23

DNA Methylation: Structures, Functions and Regulation

Amount
$388K
Period
1993-04-012017-07-31
PIs
1
Est. capacity / PI
~0 students

Awarded at EMORY UNIVERSITY

NIH #5R01GM106218-03

Novel Pharmacological Probes Targeting Exchange Proteins Activated by cAMP (EPAC)

Amount
$308K
Period
2013-04-012017-03-31
PIs
2
Est. capacity / PI
~0 students

Awarded at UNIVERSITY OF TEXAS MED BR GALVESTON

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

Potential Collaborators

Recent Publications

Last 2 years · showing 20 of 43
Open author page on OpenAlex →