Full Professor(heuristic)

Epigenetics and DNA Methylation · Molecular Biology

Compare more Molecular Biology professors.

h-index89
i10-index264
Publications510
Citations30,042

Grants

15 total · 5 active

NIH #R01AG091781

Epac1 Signaling Promotes Retinal Neuronal Injury During Tauopathy

Active
Amount
$600K–$700K
Period
2026-06-15 → 2031-03-31
PIs
2

Awarded at UNIVERSITY OF TEXAS MED BR GALVESTON

NIH #R35GM134744

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Active
Amount
$600K–$700K
Period
2020-01-01 → 2030-03-31
PIs
1

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #R01DK136462

Significance of Epac signaling in renal Na+handling and hypertension

Active
Amount
$600K–$700K
Period
2024-08-19 → 2028-06-30
PIs
2

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

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All Grants

15 total · 5 active

NIH #R01AG091781

Epac1 Signaling Promotes Retinal Neuronal Injury During Tauopathy

Active
Amount
$600K–$700K
Period
2026-06-15 → 2031-03-31
PIs
2

Awarded at UNIVERSITY OF TEXAS MED BR GALVESTON

NIH #R35GM134744

Epigenetic regulations of DNA and histone methylation and deMethylation: Structures and Mechanisms

Active
Amount
$600K–$700K
Period
2020-01-01 → 2030-03-31
PIs
1

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #R01DK136462

Significance of Epac signaling in renal Na+handling and hypertension

Active
Amount
$600K–$700K
Period
2024-08-19 → 2028-06-30
PIs
2

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #R01EY033319

Epac1 as a novel therapeutic target for diabetic retinopathy

Active
Amount
$500K–$600K
Period
2022-09-01 → 2027-06-30
PIs
2

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #R01DK132286

Mutual reinforcement between somatic mutations and transcription factors in clonal hematopoiesis

Active
Amount
$400K–$500K
Period
2023-03-01 → 2026-12-31
PIs
2

Awarded at TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR

NIH #R21CA277152

Preclinical studies of non-nucleoside DNMT3A/3B inhibitors

Amount
$200K–$300K
Period
2023-12-19 → 2025-11-30
PIs
2

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #R56DK136462

Significance of Epac signaling in renal Na+ handling and hypertension

Amount
$100K–$200K
Period
2023-08-15 → 2024-07-31
PIs
2

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #P30CA016672

25 Cancer Genetics and Epigenetics

Amount
<$100K
Period
1996-08-28 → 2024-06-30
PIs
1

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #R35GM122536

Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics

Amount
$400K–$500K
Period
2017-07-01 → 2022-06-30
PIs
1

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #R01GM049245

DNA Methylation: Structures, Functions and Regulation

Amount
$400K–$500K
Period
1993-04-01 → 2020-07-31
PIs
1

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #R01GM066170

Epac/cAMP-GEF, A Novel Intracellular cAMP Receptor

Amount
$300K–$400K
Period
2003-05-01 → 2019-04-30
PIs
1

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #R01GM114306

Histone Lysine deMethylation: Structures, Inhibitions and Mechanisms

Amount
$300K–$400K
Period
2015-04-01 → 2019-03-31
PIs
1

Awarded at UNIVERSITY OF TX MD ANDERSON CAN CTR

NIH #R01AI111464

Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

Amount
$1M–$2M
Period
2014-04-10 → 2019-03-31
PIs
2

Awarded at UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

NIH #R01GM106218

Novel Pharmacological Probes Targeting Exchange Proteins Activated by cAMP (EPAC)

Amount
$300K–$400K
Period
2013-04-01 → 2017-03-31
PIs
2

Awarded at UNIVERSITY OF TEXAS MED BR GALVESTON

NSF #0003815

U.S.-Japan Cooperative Science: Structural Analysis of Histamine N-methyltransferase and Development of Specific Inhibitors for Clinical Use

Amount
<$100K
Period
2001-04-01 → 2005-03-31
PIs
1

Awarded at Emory University

Recent Public Signals

  1. New NIH award: Epac1 Signaling Promotes Retinal Neuronal Injury During Tauopathy2026-06-15
  2. New paper: Evaluation of a multifunctional traction device for lumbar disc herniation: a prospective randomized controlled study using magnetic resonance imaging and clinical assessment (International Orthopaedics)2026-05-11
  3. New preprint: Fundamental limits on taming infectious disease epidemics2025-09-15

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Data Freshness

  • Publications as of 2026-07-09
  • Grants as of 2026-09-01

Data may not be current

Find elsewhere

Institution / lab homepage Search on ResearchGate

ORCID: 0000-0002-6967-6362

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Career Trajectory