Yin Shen

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• High-throughput PRIME-editing screens identify functional DNA variants in the human genome

  UNC Libraries · 2025-10-21

• Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath

  UNC Libraries · 2025-10-17

• Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

  UNC Libraries · 2025-10-17

• Single-cell polygenic risk scores dissect cellular and molecular heterogeneity of complex human diseases

  Nature Biotechnology · 2025-07-25 · 10 citations

• Capture-C MPRA: A high-throughput method to simultaneously characterize promoter interactions and regulatory activityPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-06-14 · 3 citations

• Comparative characterization of human accelerated regions in neurons

  Nature · 2025-02-26 · 22 citations

• Author response: The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2

  2025-02-04

• The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2

  eLife · 2025-02-04

• Author Correction: Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery

  Nature Neuroscience · 2024-12-16 · 1 citations

• The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2Preprint

  eLife · 2024-12-05 · 1 citations

• Author response: The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2

  2024-12-05

• Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery

  Nature Neuroscience · 2024-12-01 · 30 citations

• De novo structural variants in autism spectrum disorder disrupt distal regulatory interactions of neuronal genesPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2024-11-07 · 6 citations