Yuanxin Xi

Career Trajectory

Research Cluster Map

Direct collaborators. Node size = influence, colour = community, dashed = past collaboration.

• Abstract 4550: Tumor cell surface targeting of high-grade neuroendocrine carcinomas

  Cancer Research · 2026-04-03

• Abstract 4127: Inferring transcriptomic programs from circulating tumor DNA methylation signatures in small cell lung cancer using RRBS and EM-seq

  Cancer Research · 2026-04-03

• YAP1 defines an emergent, plastic population of relapsed small cell lung cancerPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-10-22

• Author response: Acquired resistance to sotorasib in KRASG12C mutant NSCLC is vulnerable to PI3K-mTOR pathway inhibition mediated by 4E-BP1 regulator of cap-dependent translation

  2025-08-22

• Acquired resistance to sotorasib in KRASG12C mutant NSCLC is vulnerable to PI3K-mTOR pathway inhibition mediated by 4E-BP1 regulator of cap-dependent translation

  eLife · 2025-08-22 · 2 citations

• Acquired resistance to sotorasib in KRASG12C mutant NSCLC is vulnerable to PI3K-mTOR pathway inhibition mediated by 4E-BP1, a regulator of cap-dependent translation

  eLife · 2025-08-22

• Combination Surface Targeting Strategies in Relapsed Small Cell Lung Cancer (SCLC) to Overcome Intratumoral Heterogeneity Associated with Treatment Resistance

  Journal of Thoracic Oncology · 2025-08-01

• Antitumor Activities of HER2- and TROP2-Directed Antibody Drug Conjugates in Recalcitrant Pulmonary High-Grade Neuroendocrine Carcinomas

  Journal of Thoracic Oncology · 2025-08-01

• Data from Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to ImmunotherapyPreprint

  2025-06-02 · 2 citations

• Supplementary Data from Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to ImmunotherapyPreprint

  2025-06-02

• NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck CancerPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-04-29 · 2 citations

• Abstract 2931: AXL-directed surface targeting approaches in recalcitrant pulmonary high-grade neuroendocrine carcinomas

  Cancer Research · 2025-04-21

• Abstract 5517: Overcoming sotorasib acquired resistance in KRASG12C mutant NSCLC by TUSC2 gene therapy

  Cancer Research · 2025-04-21

• Abstract 2928: Combination surface targeting strategies in relapsed small cell lung cancer (SCLC) to overcome intratumoral heterogeneity associated with treatment resistance

  Cancer Research · 2025-04-21

• DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer

  Molecular Cancer · 2025-03-20 · 8 citations

• Acquired resistance to sotorasib in <i>KRAS</i> ^<i>G12C</i> mutant NSCLC is vulnerable to PI3K-mTOR pathway inhibition mediated by 4E-BP1, a regulator of cap-dependent translationPreprint

  bioRxiv (Cold Spring Harbor Laboratory) · 2025-03-19

• Mutation of SMARCA4 Induces Cancer Cell–Intrinsic Defects in the Enhancer Landscape and Resistance to Immunotherapy

  Cancer Research · 2025-03-13 · 14 citations

• YAP1 Defines an Emergent, Plastic Population of Relapsed Small Cell Lung CancerPreprint

  Journal of Thoracic Oncology · 2025-01-01

• Supplementary Figure S4 from YAP1 Status Defines Two Intrinsic Subtypes of LCNEC with Distinct Molecular Features and Therapeutic VulnerabilitiesPreprint

  2024-10-15

• Supplementary Figure S6 from YAP1 Status Defines Two Intrinsic Subtypes of LCNEC with Distinct Molecular Features and Therapeutic VulnerabilitiesPreprint

  2024-10-15